基因组技术基础

1202 次查看
约翰霍普金斯大学
Coursera
  • 完成时间大约为 8 个小时
  • 混合难度
  • 英语
注:本课程由Coursera和Linkshare共同提供,因开课平台的各种因素变化,以上开课日期仅供参考

课程概况

This course introduces you to the basic biology of modern genomics and the experimental tools that we use to measure it. We’ll introduce the Central Dogma of Molecular Biology and cover how next-generation sequencing can be used to measure DNA, RNA, and epigenetic patterns. You’ll also get an introduction to the key concepts in computing and data science that you’ll need to understand how data from next-generation sequencing experiments are generated and analyzed.

This is the first course in the Genomic Data Science Specialization.

课程大纲

Overview

In this Module, you can expect to study topics of "Just enough molecular biology", "The genome", "Writing a DNA sequence", "Central dogma", "Transcription", "Translation", and "DNA structure and modifications".

Measurement Technology

In this module, you'll learn about polymerase chain reaction, next generation sequencing, and applications of sequencing.

Computing Technology

The lectures for this module cover a few basic topics in computing technology. We'll go over the foundations of computer science, algorithms, memory and data structures, efficiency, software engineering, and computational biology software.

Data Science Technology

In this module on Data Science Technology, we'll be covering quite a lot of information about how to handle the data produced during the sequencing process. We'll cover reproducibility, analysis, statistics, question types, the central dogma of inference, analysis code, testing, prediction, variation, experimental design, confounding, power, sample size, correlation, causation, and degrees of freedom.

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