为什么我们会变老?衰老的分子机制

Why Do We Age? The Molecular Mechanisms of Ageing

Why do we age? Is there a limit to human lifespan? Can we prolong our lives? Find out with this free online course.

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荷兰格罗宁根大学
FutureLearn
  • 完成时间大约为 6
  • 初级
  • 英语
注:本课程由FutureLearn和Linkshare共同提供,因开课平台的各种因素变化,以上开课日期仅供参考

你将学到什么

Explain the main theories and mechanisms of ageing

Describe the processes that are happening in the ageing cells

Discuss the use of different model organisms to study human ageing

课程概况

The “why” and “how” of ageing has puzzled mankind ever since it questioned its place in the universe.

However, it was only after infectious diseases became more controlled and reliable food supplies became generally available, that the rapid increase of the average lifespan made science turn its attention to study longevity and ageing.

To fulfil the desire to live longer and age healthier, it is essential that we better understand the intricate molecular processes that evolve in our body when we age.

Study the concepts and theories of ageing

In this free online course, you will study the current concepts and theories of ageing. You will learn about the molecular and cellular processes in ageing. You will explore the cell systems, animal models and advanced experimental methods that we use to study ageing.

After introducing the main theories and mechanisms of ageing in the first week, we will proceed with a series of in-depth lectures from distinguished researchers working at the European Research Institute for the Biology of Ageing at the University of Groningen. They will present you with a selection of their current research and will explain the fundamental questions they try to answer and the experimental approaches they use for their studies.

You will learn that ageing starts at the cell level and you will study several phenomena which take place in cells, such as genomic instability, telomere shortening and epigenetic changes.

By completing this course you will gain insight into the fundamental biology of ageing in various simple and complex organisms, including humans.

课程大纲

Cellular ageing

Chromosomes and ageing

Genomic instability and epigenetics

Stem cells in ageing and rejuvenation

Molecular aspects of health and disease during ageing

Genetics and evolution of ageing

面向人群

The course is aimed at anyone interested in understanding the biology of ageing. It requires basic knowledge of biology, though most of the terms are explained and you will receive further support via additional reading.

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